Transcriptional elongation by RNA polymerase II (Pol II) is usually regulated by positive transcription elongation factor b (P-TEFb) in association with bromodomain-containing protein 4 (BRD4). important role in regulating lineage-specific gene transcription in human CD4+ T cells. assays show that BRD4 binding can be supported by diacetylated histone 3 (H3) at lysines K9/14, and by […]