Protease-activated receptor-1 (PAR1) contains five the surface of ECL2 serves distinct functions critical for proper regulation of receptor trafficking and the fidelity of thrombin signaling. the carboxyl amide and purified by reverse phase-high pressure liquid chromatography at Tufts University Core Facility (Boston). PNGase F sialidase and endoglycosidase H were purchased from New England Biolabs Inc. […]