Caveolin-1 (Cav) a primary protein component of caveolae is overexpressed in prostate Bay 65-1942 cancer thereby promoting growth and metastasis of this tumor. cells which was blocked by treatment with 1 or 10 nM PEDF or following the overexpression of small interfering RNAs directed against Cav. Cav (10 nM) increased DNA synthesis in PC-3 cells […]